Jennifer Weiner discusses Oprah Winfrey's recent weight loss announcement. Oprah has achieved her goal weight again, using a new weight-loss drug, strict diet, and exercise routine. Weiner empathizes with Oprah's struggles, acknowledging the societal pressure on women regarding weight and the constant battle to maintain a certain body image. She relates to Oprah's experiences as a larger woman and emphasizes the mental and emotional toll of weight fluctuations. This resonates with Weiner and many others who have faced similar challenges.